Finasteride should be the last resort, not the go-to.
In the present study, finasteride is seen to have caused DNA damage and menstrual bleeding in women who used finasteride (5 mg/day) as compared with women who did not use it. The enzyme 5-α reductase is produced in many male and female tissues like the reproductive tract, testes and ovaries.
Also, some other studies considered SAA gene as stress protein marker for DNA damage and cancer, which also support our findings on the DNA damage. Furthermore, Alkahtane et al. were recently found that finasteride administration to female mice has adverse effects within both the short and the long periods in female mice associated with apoptosis induction. Tu and Zini also reported that low-dose finasteride may exert a harmful influence on sperm DNA integrity and sperm DNA injure in men, resulting in increased pregnancy losses.