The appetite genes: Why some of us are born to eat too much

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YOU’VE just finished an indulgent meal, the plates have been cleared and you sit back in your seat, stuffed. You couldn’t possibly manage another bite. But then it turns out they have sticky toffee pudding, your favourite dessert. Oh go on then, you can make room.

We all succumb to temptation. And it’s no secret that people have big differences in appetite – some eat like birds, others like horses. But only some of these differences reflect our energy needs.

The driving factors for weight gain tend to get oversimplified: studies show that most people still think obesity is down to laziness and gluttony. Others tend to shrug and blame “big bones” or “bad genes”.

Genes play a part: they may be responsible for as much as two-thirds of our variation in weight. But they aren’t betraying us in the way many assume. Some slow down our metabolic rate, leading to a build-up of fat, but they are the exception. Instead, most make people chubby in a more insidious way: by subtly affecting how appealing food seems to us, and how quickly we feel full.


Not only that, but these genetic effects kick in even from the first weeks of life. In other words, the deck may be stacked against you right from the start. Understand that, and we may each have the key to maintaining a healthy weight – and might finally make inroads against the obesity epidemic.

Measuring how our response to appealing food and to feelings of fullness can influence weight is something that can be traced back to 2007. That’s when the …

https://www.google.co.uk/amp/s/www....-why-some-of-us-are-born-to-eat-too-much/amp/
 
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